Phenotypic transition
Webn. 1. a. The observable physical or biochemical characteristics of an organism, as determined by both genetic makeup and environmental influences. b. The expression of … Web1. máj 2012 · The ability to switch between different phenotypic forms has been thought to contribute to its virulence. The yeast-filamentous growth transition and white-opaque switching represent two typical …
Phenotypic transition
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Web11. dec 2024 · Adaptive Transition Proceeds Through Drug-Mediated Cell State Interconversion and Phenotypic Selection. Three factors can account for the drug-induced cell state transition kinetics. The first is a deterministic factor that arises from cell state changes determined by the underlying causative gene regulatory networks. WebIndeed, spontaneous phenotypic transitions are extremely rare. However, stochastic noise provides an unbounded perturbative force that drives the cell from one state to others [ 9 …
WebA key example is the phenotypic transition of fibroblasts to myofibroblasts. Fibroblasts transform from a role of quiescent maintenance to one of active extracellular matrix … Web14. sep 2024 · The phenotypic transition is regulated by numerous modulators. This review focus on the literature regarding the modulators and signaling pathways involved in …
WebMacrophages play an important role in the immune microenvironment during bone healing, and sequential macrophage phenotypic transition could achieve superior osteogenic … WebWe have previously shown that treatment of breast cancer cells with taxanes can induce a phenotypic transition, converting a CD44 Lo to CD44 Hi phenotype and conferring a transient tolerance to taxanes (5, 15), which we characterized using mathematical models as a metastable hybrid state ().These drug-tolerant cells are cross-tolerant to other …
Web3. okt 2024 · Phenotype transition takes place in many biological processes such as differentiation and reprogramming. A fundamental question is how cells coordinate …
WebWe also discover that the sets of developmental parameters involved in tooth shape transitions tend to depend asymmetrically on the direction of that transition. Together, our findings provide a valuable base for furthering our understanding of how developmental changes can lead to both adaptive phenotypic change and trait convergence in ... reliability threats in researchWeb22. dec 2024 · Vascular smooth muscle cells (VSMCs) are involved in phenotypic switching in atherosclerosis. This switching is characterized by VSMC dedifferentiation, migration, … reliability theory pdfWeb20. júl 2024 · Mechanistically, activation of the PI3K/Akt/mTOR pathway promotes the phenotypic transition from suspension to adhesion growth pattern and confers SCLC … product think tank waitsfieldWebThe primary finding of the present study is that a short-term community exercise intervention positively transitions individuals across the phenotypic spectrum from MAO … product tieins tobaccoWeb28. júl 2024 · The abnormal proliferation, migration, and phenotypic transition of vascular smooth muscle cells (VSMCs) played a crucial role in the initiation and progression of aortic dissection, with 5′-tiRNA-Cys-GCA as a potential phenotypic switching regulator, because its overexpression inhibited the proliferation and migration of VSMCs and increased the … product tinsWebFINE-SCALE PHENOTYPIC CHANGE ACROSS A SPECIES TRANSITION ZONE IN THE GENUS NEOTOMA: DISENTANGLING INDEPENDENT EVOLUTION FROM PHYLOGENETIC HISTORY Marjorie D. Matocq1,2 and Peter J. Murphy1,3 1Department of Biological Sciences, Idaho State University, Pocatello, Idaho 83209 2E-mail: [email protected] 3E-mail: … product ticketWeb14. okt 2024 · The epithelial–mesenchymal transition (EMT) is a cellular programme on which epithelial cells undergo a phenotypic transition to mesenchymal ones acquiring metastatic properties such as mobility and invasion. TGF-β signalling can promote the EMT process. However, the dynamics of the concentration response of TGF-β-induced EMT is … product tier naming