Cynomolgus monkey body temperature

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August undefined, 2024

WebBody temperature of cynomolgus macaques, rhesus macaques and common marmosets before and after Mex4487 influenza virus infection. (A) Circadian temperature pattern, … WebApr 2, 2015 · Cynomolgus monkeys (Macaca fasicularis)(Covance Research Products, Emeryville, CA) were simple housed for a colony room down a 12-h light-dark cycle, 50% (± 30%) humidity, and 22°C (± 2°C). Related food, aquarium, treats, both vitamin supplements were provided, and animals were given admission to environmental enrichment such as …

Biology and Medicine of Non-human Primates. Part II: Clinical

WebFeb 18, 2024 · Six males and 4 females colony Chinese cynomolgus monkeys (Macaca fascicularis) were selected for this study. The animals were between 5.2 and 6.9 years old. Body weights ranged between 5.2 and 9.6 kg and between 3.6 and 5.2 kg for males and females, respectively. WebThe estimated volumes were 106 ml for a 3 kg cynomolgus monkey, which is comparable to-but lower than the cynomolgus blood volumes reported in the literature (65 ml/kg) (26). This indicated... cleaning electric fan with hose

Normal Anatomy, Histology, and Spontaneous Pathology of the …

WebElectrocardiograms (ECGs), hemodynamic parameters (diastolic, systolic, and mean arterial pressures) as well as core body temperatures were recorded for 22 h from each of 99 … WebSep 15, 2024 · Body temperature was examined before dosing (pre), at 30 min, 1, 2, 4, 8, 24, 32, 48, 54, and 72 h after dosing. Serum cytokine concentrations were examined on Pre 1, Pre 2 (pre, 2, 8, 24 h), Days 1 (pre, 2, 8 h), 2, and 3. Animals were sacrificed on Day 3 after 1000 μg/kg, on Day 10 after 10 μg/kg, and on Day 24 after 100 μg/kg. 2.4. WebBody temperature (A) and activity (B) of rhesus monkeys were monitored. The onset of fever was observed (arrowheads). ... 44 Two cynomolgus monkeys were intravenously administered with rMV ... downwash and induced drag

Tissue Physiology of Cynomolgus Monkeys: Cross-Species

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WebAug 14, 2024 · Herein we report on neurological signs that have been observed in 28 IT studies conducted in 1,016 cynomolgus monkeys. Neurological signs were classified into 5 groups: (1) A nonadverse transient absence of lower spinal reflexes. This observation occurred at low incidence in nontreated animals and in those that were injected artificial ... WebBody temperature of cynomolgus macaques, rhesus macaques and common marmosets before and after Mex4487 influenza virus infection. (A) Circadian temperature pattern, shown for two animals of... cleaning electric guitar stringsWebSep 15, 2024 · Peak cytokine levels following the single and ascending doses were 60,095 pg/mL and 1221 pg/mL for IL-6; 353 pg/mL and 14 pg/mL for TNF-α; 123 pg/mL and 16 pg/mL for IFN-γ; and 2219 pg/mL and 42 pg/mL for IL-2. The tolerance acquired with daily ascending doses up to 1000 μg/kg remained in effect for the following weekly doses of … cleaning electric hair clippers

"WebApr 5, 2007 · Methods Body temperatures of 51 cynomolgus macaques were taken with rectal thermometry and non-contact infrared thermometry (NIFT) on the shoulder, face, abdomen, and axillary region. Results and conclusions Body temperature measurements from NIFT were statistically different ( P < 0.0001) from rectal thermometry. " - Cynomolgus monkey body temperature

Cynomolgus monkey body temperature

Daily ascending dosing in cynomolgus monkeys to mitigate

WebMar 27, 2024 · Furthermore, our results suggest that AANAT, melatonin synthetic enzyme, is also expressed in cynomolgus monkey cumulus cells and oocytes at GV- and MII-stages (Figures 1 and 2), indicating that melatonin synthesis may occur in cynomolgus monkey oocytes during meiotic maturation. To confirm the role of melatonin during … Ninety-nine cynomolgus monkeys (58 M, 41 F) were equipped with radiotelemetry … A pooled community-based population sample of 17,139 North American … The adequacy of the Bazett formula to correct for heart rate-induced changes in … Five male cynomolgus monkeys weighing 4.0 to 6.0 kg supplied by Keari, were … Three frequently used and cited formulas used to rate correct the QT interval … Dependence of QT interval duration on cardiac heart rate has been well …

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WebOct 26, 2024 · The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected billions of individuals and is the cause of the current global coronavirus disease 2024 (COVID-19) pandemic. We previously developed an mRNA vaccine (LVRNA009) based on the S protein of the Wuhan-Hu-1 strain; the phases I and II clinical trials … Webwarmed (body temperature) fluids. Intradermal volume for all species was of 0.05-0.1 ml with adjuvant, dependent on the thickness of the skin. Subcutaneous and intramuscular dosing is limited to two sites per day. ... Cynomolgus monkey) and primate (small- e.g., marmoset). The routes included oral, subcutaneous, intraperitoneal,

WebJan 6, 2006 · The daily time budget and movement patterns of long-tailed macaques involve traveling, feeding, resting and socializing. Long-tailed macaques have a home range size of about 1.25 km² (.58 mi²) and daily path length varies greatly between 150 and 1900 m (.09 and 1.18 mi) (Wheatley 1980; Rowe 1996). WebApr 5, 2007 · Methods Body temperatures of 51 cynomolgus macaques were taken with rectal thermometry and non-contact infrared thermometry (NIFT) on the shoulder, face, …

WebWith the implanted device, blood pressure and core body temperature can be monitored simultaneously. Despite the frequent use of cynomolgus monkeys in nonclinical safety … WebFeb 24, 2024 · Weight and body temperature were monitored daily ... rhesus and cynomolgus monkeys. Virology 330, 8–15 (2004). Article CAS Google Scholar ...

WebMar 2, 2016 · For the cynomolgus monkey ... The temperature and humidity were automatically controlled at 21°C ± 4°C and 55% ± 10%, respectively, with a minimum of 15 air changes per hour. An automatic light cycle of 7:00 a.m. to 7:00 p.m. (20-hr cycle) was maintained. ... Soon after euthanasia, the heads of the monkeys were removed from the …

WebFeb 24, 2024 · Weight and body temperature were monitored daily ... rhesus and cynomolgus monkeys. Virology 330, 8–15 (2004). Article CAS Google Scholar ... cleaning electric coffee potWebRespiration rate, heart rate, and body temperature values were obtained from 14 cynomolgus monkeys ( Macaca fascicularis) during neurosurgery under barbiturate … cleaning electric kettle insideWebMacaca fascicularis (cynomolgus) The Wisconsin National Primate Research Center is home to about 1,130 rhesus monkeys and 220 cyno-molgus monkeys. The genus … downwash ductsWebDec 27, 2016 · Cynomolgus monkey studies Groups (two or three animals/group) of male and female cynomolgus monkeys were given 0, 5, 15, 45 or 135 μg/kg/day of BI 836909 via continuous intravenous infusion... downwash derivative formulaWebAug 1, 2024 · The standard points in 100% cynomolgus monkey serum range from 2,560 ng/mL to 10.0 ng/mL, and the range of quantitation in 100% serum is 1,280 ng/mL to 40.0 ng/mL. Five samples ipilimumab and nivolumab at 1,280, 640, 160, 80, and 40 ng/mL serve as quality control samples. cleaning electric guitar potsWeb1 day ago · Cynomolgus monkeys represent an appropriate species to assess the toxicological profile of IL-12. 10, 27 To confirm that cynomolgus monkeys respond to DF6002 similarly to rhIL ... DF6002 was well tolerated at 19 μg/kg in cynomolgus monkeys, as measured by body temperature and blood pressure or the CNS or … cleaning electric coffee pot with vinegarWebJun 9, 2016 · Animals were housed in an air conditioned room in the following ambient conditions: 22°C ± 2°C temperature, 15–20 air … cleaning electric kettle with lemon